AMIA 2025 Informatics Summit Call for Participation

Dive into the creation of storage, analytical, and interpretive methods designed to optimize the transformation of an ever-growing volume of biomedical data, including genomic/omics data, into proactive, predictive, preventive, and participatory health. This track focuses on the development of innovative techniques for the integration and interpretation of biological and clinical data, and the evolution of clinical informatics methodology to propel precision medicine initiatives. The ultimate goal of translational bioinformatics is to generate actionable data and newfound knowledge from these integrative efforts, benefiting a wide range of stakeholders, including bioinformaticians, biomedical scientists, clinicians, and patients.

Explore the application of informatics in the discovery and management of new knowledge relating to health and disease, with a particular emphasis on generating real-world evidence. This track covers the management of information related to clinical trials and extends to informatics associated with secondary research use of clinical data. Clinical research informatics serves as a pillar of informatics activities bolstering translational research. These fields play a pivotal role in shaping real-world evidence that not only informs policy making but also influences practices in the pharmaceutical and insurance industries. The insights derived have the potential to revolutionize health system practices, leading to improved patient outcomes and more efficient healthcare delivery.

Advance the science and art of creating data-driven solutions, harnessing the power of generative AI, reinforcement learning, and large language models, to unravel complex real-world health problems. Health Data Science and AI is a rapidly expanding field at the intersection of statistics, computer science, and biomedicine. Addressing intricate biomedical data and ethics challenges often calls for integrative approaches, combining specialized domain knowledge with emerging methods from a diverse range of fields.

This theme would explore how translational bioinformatics increasingly propels precision medicine. It would focus on the integration and interpretation of diverse data types - from omics to clinical and imaging data - combined with AI and machine learning-based predictive models to create a comprehensive understanding of health and disease at an individual level.

This theme would explore methods and algorithms, including AI- and machine learning-based models, for variant detection and clinical variant interpretation from genomic data. It would explore methods and web-based tools for discovery, accessibility, and application in research and clinical settings.

This theme would address serving the biomedical research enterprise at scale with informatics. Topics include but are not limited to sustainability, build-versus-buy, vendor engagement and procurement, on-premises and cloud storage and compute, enterprise data warehouse for research (EDW4R) operations, governance, regulatory, privacy, data sharing, and industry partnerships.

This theme would explore the role of digital health technologies–apps, wearables, and websites among others–in engaging patients for research, measuring patient-reported outcomes, and collecting and leveraging patient-generated data. Strategies for enabling DHTs at scale and integrated with clinical care to harness patient-generated data for research are of particular interest.

From Single-Center to Multi-Site: This theme would address approaches to analytics, data, statistics, natural language processing, data literacy, workforce development, workflow, and policy from individual healthcare organizations and large scale multi-institutional patient data sharing initiatives like PCORnet, N3C, Cosmos, eMERGE, and TriNetX among others. The theme would include methods and lessons learned for measuring patients outcomes, limiting bias, ensuring fairness, addressing disparities, and promoting equity.

This theme would focus on the strengths and limitations of large language models in extracting knowledge from complex health data, and the potential of these tools to reshape informatics and biomedicine as well as ethical and safety concerns.

Bridging the Gap between Research and Practice: This theme would explore how real-world evidence generated through informatics is informing policy making, influencing the pharmaceutical and insurance industries, and leading to improvements in health system practices.

The Power of Generative AI and Reinforcement Learning: This theme would delve into the proactive capabilities of generative AI and reinforcement learning in driving biomedical advancements. From generating synthetic data and discovering new drugs to personalizing medicine, influencing behavioral change, and optimizing treatments, these proactive machine learning techniques may accelerate innovation across clinical and translational science.

Enabling Clinical and Translational Research: This theme would delve into the practical aspects of applying informatics in the biomedical research enterprise rather than clinical care. It would highlight the importance of implementation science in ensuring the successful deployment of informatics solutions, focusing on strategies for overcoming barriers, enhancing adoption, and achieving meaningful impact for clinical and translational research and science.

This theme would explore translation from bench to bedside through EHR system configuration, optimization of clinical trials accrual and recruitment with informatics interventions, strategies for informed consent of research participants at scale, and managing and leveraging biospecimens linked to EHR data, including return of result workflows.

• Advanced data visualization tools and techniques
• Bioimaging techniques and applications
• Biomarker discovery and development
• Biomedical informatics and data science workforce education
• Citizen Science and democratization of AI and informatics
• Clinical decision support for translational/data science interventions
• Clinical genomics/omics and interventions based on omics data
• Clinical and research data collection, curation, preservation, or sharing
• Clinical trials innovations
• Cohort discovery
• Collaborative workflow systems
• Data commons
• Data-driven research and discovery
• Data Integration
• Data Literacy and numeracy
• Data/system integration, standardization and interoperability
• Data mining and knowledge discovery
• Data quality
• Data security and privacy
• Data sharing / interoperability
• Data standards
• Data transformation/ETL
• Digital research enterprise
• Drug discovery, repurposing, and side-effect discovery
• Education and Training
• EHR-based phenotyping
• Enterprise data warehouse/Data lake
• Epigenomics
• Ethical, Legal, and Social Issues
• Exposome and Data Integration
• Fairness and disparity research in health informatics
• FHIR
• Genomic/Omic data interpretation
• Genotype-phenotype association studies (including GWAS)
• Geographical information systems (GIS)
• Health Information and biomedical data dissemination strategies
• Health literacy issues and solutions
• Implementation Science and Deployment
• Infectious disease modeling
• Influence of informatics on pharma and insurance industry
• Informatics for cancer immunotherapy
• Informatics research/biomedical informatics research methods
• Integrative omic analysis
• Knowledge representation, management, or engineering
• Learning healthcare system
• Machine learning, Generative AI, and predictive modeling
• Medical Imaging
• Measuring outcomes
• Mobile Health, wearable devices and patient-generated health data
• Natural Language Processing
• Ontologies
• Open Science for biomedical research and translational medicine
• Outcomes research, clinical epidemiology, population health
• Patient centered research and care
• Pharmacogenomics
• Phenomics and phenome-wide association studies
• Proactive machine learning and reinforcement learning
• Public health informatics
• Real-world evidence and policy making
• Recruitment technologies
• Reproducible research methods and tools
• Single Cell Analysis
• Secondary use of EHR data
• Social determinants of health
• Stakeholder (i.e., patients or community) engagement
• Sustainable research data infrastructure
• Systems biology and network analysis
• Transcriptomics

The SPC solicits paper proposals both on fundamental informatics methods as well as systems and applications. Proposals must not be in press or under consideration for presentation or publication elsewhere. However, authors retain the right to make a pre-print version of the paper available on recognized preprint servers or personal/employer websites prior to acceptance for publication. Authors must adhere to the formatting guidelines to avoid rejection.

Manuscripts must be formatted to fit on between 5-10 (8.5 x 11 inch) pages and include:

• The names, academic degree(s), affiliations, and locations (city, state, and country, if international) of all authors
• Introduction, methods, results, discussion, and conclusion sections
• A structured manuscript must be submitted that includes the following sections:
• An abstract of 125-150 words summarizing the submission. The abstract must also be entered on the submission website in the Abstract box in Step 1.
• Introduction – A short background and objective(s) of the study
• Methods – Design, setting (if appropriate), patients or participants (if appropriate), interventions (if appropriate), and main outcome measurement
• Results – Key findings
• Discussion – Key conclusions with direct reference to the foundational or methodological advancement or biomedical application
  • Optional illustrations (figures or tables)
  • References, if applicable

The SPC invites students to submit papers that describe complete or nearly complete research or development efforts in informatics. All designated student papers must follow the paper format requirements (see above) and will first be reviewed through the SPC’s standard review process, along with all other submitted papers. Student papers that are accepted by the SPC will be presented in a regular paper session and included in the Informatics Summits Proceedings. Proposals must not be in press or under consideration for presentation or publication elsewhere. However, authors retain the right to make a pre-print version of the paper available on recognized preprint servers or personal/employer websites prior to acceptance for publication. Papers can only be submitted as a student paper or a regular paper, not both.

Individuals, who as of September 1, 2022, are enrolled in a degree granting program or in an academic program such as a medical residency or a post-doctoral fellowship, are eligible to submit a student paper. Work performed as part of a large, collaborative effort is acceptable; however, the student paper will be judged on the student’s specific contributions to the project, which must be clearly delineated. Only individual students, not groups, may submit student papers. Preparation of a manuscript must be entirely the work of the student, and single authorship is strongly encouraged. Co-authorship is usually limited to the student’s academic advisor. Entries from international students are encouraged. Student papers must adhere to the same requirements as described in the papers category, and in addition, student authors must provide in the online form:

• The name and address of the training program
• Clear identification of the primary advisor/mentor of the student submitting the paper
• All co-authors and a description of that particular author’s contribution to the work
• An attestation of the student’s contribution to the manuscript with respect to the following items:
  • (a) The text of the manuscript itself;
  • (b) The data collected for any analysis;
  • (c) The actual data analysis;
  • (d) The review of the literature;
  • (e) If a system was developed, the role of the student in the coding/development of the system; and
  • (f) The evaluation of the results and the formation of the conclusion
• The student will be asked to upload a PDF of the attestation letter signed by their primary advisor confirming items a-f above

The podium abstract format allows for the presentation of cutting-edge unpublished research that the author wishes to reserve publication rights for future consideration or outstanding work previously published in a peer-reviewed journal. Priority will be given to previously unpublished work. Authors of accepted podium abstracts will have up to 18 minutes to present their work at the symposium including any questions and discussion.

Abstracts will not be indexed in MEDLINE, enabling authors to submit their best work that is destined for future journal publication. Contributions may also consist of abstracts based on work published in peer-reviewed journals in the last year (i.e., publication after August 2020); however, works published as proceedings for other conferences will not be accepted. Citation of the previous work is required.

Submissions must be submitted as a two-page (including all tables, figures, references, and acknowledgements) (U.S. Letter; 8.5 x 11 inch) document and include:

The names, academic degree(s), affiliations, and locations (city, state, and country, if international) of all authors.

A structured abstract must be submitted that includes the following sections:

• Introduction – A short background and objective(s) of the study;
• Methods – Design, setting (if appropriate), patients or participants (if appropriate), interventions (if appropriate), and main outcome measurement;
• Results – Key findings;
• Discussion – Key Conclusions with direct reference to the foundational advancement or biomedical application of the work;
• Optional illustrations (figures or tables);
• References.

All podium abstract submissions must have a brief (50-75 words) abstract. The abstract paragraph does NOT have to be part of the document but must be entered on the submission website in the online submission form.

Posters are the preferred format for presenting preliminary research results or results of small-scale studies. With the poster, authors illustrate and discuss innovative systems and services; describe experimental and in-practice projects and programs; and report experiences with educational programs and other dimensions of informatics. The poster sessions are vibrant and popular components of the Summit, offering direct access to the authors in a way not possible through podium presentations. At least one author must be present at the poster session.

Your uploaded poster manuscript file must be submitted as a one-page (8.5 x 11 inch) document and must include:

• The names, academic degree(s), affiliations, and locations (city, state, and country, if international) of all authors.
• A description of the problem addressed and specific purposes of the system, service, or project; or, in the case of original research, an overview of the methodology, evaluation results, and conclusions
• Optional illustrations (figures or tables), which must fit in the one-page limit
• References, if applicable
• Accepted posters will be presented on poster boards which are 8’ high by 4’ wide
• All poster submissions must have a brief (50-75 words) abstract. The abstract does NOT have to be part of the document but must be entered on the submission website in the Abstract box (please DO NOT copy and paste the entire one-page document into that box).

The SPC invites students to submit posters. Posters are the preferred format for presenting preliminary research results or results of small-scale studies. With the poster, authors illustrate and discuss innovative systems and services; describe experimental and in-practice projects and programs; and report experiences with educational programs and other dimensions of informatics. The poster sessions are vibrant and popular components of the Informatics Summit, offering direct access to the authors in a way not possible through podium presentations. At least one author must be present at the poster session.

All designated student posters must follow the poster format requirements (see above) and will be reviewed through the SPC’s standard review process, along with all other submitted posters. Proposals must not be in press or under consideration for presentation or publication elsewhere. Posters can only be submitted as a student poster or a regular poster, not both.

Individuals, who as of September 1, 2022, are enrolled in a degree granting program or in an academic program such as a medical residency or a post-doctoral fellowship, are eligible to submit a student poster. Work performed as part of a large, collaborative effort is acceptable, however, only individual students, not groups, may submit student posters. Preparation of an abstract must be entirely the work of the student. Student posters must adhere to the same requirements as described in the Poster - Regular category.

Panel sessions are designed to present an integrated set of perspectives or experience on a current topic in translational science. Panel topics may be on a specific aspect of theory, application, policy, trends, or experience pertaining to any aspect of translational science, or may provide interdisciplinary viewpoints that cut across traditional themes. Panel submissions and presentations should demonstrate collective reflection and integration of the content presented by each of the panelists or offer engaged forms of dialogue and interaction between panelists and audience. Scholarly debate among presenters is encouraged, as are panels that incorporate science, practice, and policy themes to improve the conduct of clinical and translational research.

Panels should be limited to four participants and a moderator and should be timed to allow one-third to one-half of the session for audience participation. Panel organizers should include a description of how they plan to include/involve audience participation in their session. Panel sessions will typically be scheduled for 90-minutes. An individual may be the primary organizer of only one panel and may not participate on more than two panels total.

AMIA is committed to diversity, and we appreciate your efforts to select panelists with diverse institutional, gender, ethnicity, career status, and other diversity measures. Priority will be given to panels with diverse participants.

Your uploaded panel manuscript file must not exceed a maximum of three (8.5 x 11 inch) pages and must include:

• The names, academic degree(s), affiliations, and locations (city, state, and country, if international) of the panel organizer and all participants
• An abstract of 125-150 words, describing the panel and its learning objectives, which should also be entered into the Abstract text box in Step 1 of the online form to be used in the online and print programs
• A general description of the panel and the issue(s) that will be examined and a brief description of each panelist's presentation
• An explanation why the topic of this panel is timely, urgent, needed, or attention grabbing is required with a discussion of anticipated audience.
• A list of discussion questions to enhance audience participation.
• A statement from the panel organizer that all participants have agreed to take part on the panel.

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Informatics debate provides conference participants with the opportunity to use debate as a platform for presenting the pros and cons of a biomedical informatics issue. Debates can cover a wide range of topics including ethical, technology, policy, research, or otherwise-focused debates with specific implications for translational bioinformatics, clinical research informatics, or health data science. Informatics debate submissions must present a fair assessment of both the pros and cons of any topic. The debate submission should not appear biased towards one outcome. 

Informatics debate should be limited to four participants and a moderator, and they should be timed to allow for audience participation, including pre- and post-debate assessment of agreement with the debate resolutions. A good debate often has two presenters who are presenting pros and two presenters presenting cons regarding a selected biomedical issue. There will be two 45-minute debates (e.g., 30-minute participant debates and 15-minute audience engagement) in a 90-minute session. An individual may be the primary organizer of only one informatics debate and may not participate on more than two debates total.

The uploaded panel manuscript file must not exceed a maximum of three pages (including all tables, figures, references, and acknowledgements) (U.S. Letter; 8.5 x 11 inch) and include:

• The names, academic degree(s), affiliations, and locations (city, state, and country, if international) of the debate organizer and all participants;
• An abstract of 150 words, describing the informatics debate and its learning objectives, which should also be entered into a text box at the beginning of the online form to be used in the online program;
• A general description of the informatics debate and the issue(s) or position(s) that will be examined;
• Explanation of the role of each participant in the debate, including if they will take the pro or the con.
• An explanation why the topic of this informatics debate is timely and relevant to the AMIA audience;
• A description of how the audience will be engaged in the debate;
• A statement from the debate organizer that all participants have agreed to take part in the debate.

Half-day (3-hour) workshops are dedicated to in-depth treatment and collaborative discussion of special topics and interests of relevance to the broad biomedical informatics community. These workshops will be scheduled in two 90-minute slots, with a 30-minute break between.

These workshops are divided into two categories:

1. Instructional Workshops, focusing on knowledge base and competency development by participants.
2. Collaborative Workshops, intended to support the creation and ongoing activities of communities-of-practice within AMIA.

Workshops should have no more than five speakers.

Instructional Workshops should include a combination of didactic and interactive content delivery, as well as participant interaction. Such workshops should be designed to address the needs and interests of individuals at all levels of experience relative to the selected topic area(s) and be led by individuals with appropriate subject matter expertise. The SPC encourages proposals that will bring together individuals with similar or different roles in developing, implementing, or using informatics in practice, management, education, research, or policy. Further, the SPC seeks a balance between workshops that address essential core informatics theory and principles, with those that address practical applications, current issues, and emerging trends and developments in informatics, aligned with overall meeting themes.

Collaborative Workshops are intended to encourage participation and collaboration using mechanisms such as discussion forums (e.g., shorter didactic presentations or panels followed by group discussions), research forums (e.g., presentations and discussions related to scientific advancements in a targeted areas of informatics innovation and practice), or a challenge/competition (e.g., individual or group submissions addressing a specific topic or scientific/technical challenge).

The SPC may ask individuals proposing thematically similar workshops in an independent manner to integrate their submissions prior to acceptance.

AMIA is committed to diversity, and we appreciate your efforts to select participants with diverse institutional, gender, ethnicity, career status, and other diversity measures. Priority will be given to workshops with diverse participants.

Workshop proposals must not exceed a maximum of four pages (U.S. Letter; 8.5 x 11 inch) in length and include the following information:

• A descriptive title for the workshop;
• An indication of the workshop type (i.e., instructional or collaborative);
• The names, academic degree(s), affiliations, and locations (city, state/province, and country, if international) of all workshop faculty;
• A summary of 250 to 300 words that describes the content of the workshop;
• An outline of topics to be covered and description of interactive components of the workshop;
• Specific educational objectives or outcomes that participants can expect to achieve;
• A description of who should attend (e.g., clinicians, educators, leaders in healthcare or other organizations, researchers, policy makers, IT professionals);
• A description of prerequisites knowledge that participant should have, if any;
• Indicate if the workshop instructional level is introductory, intermediate, or advance or a combination. In the latter case, list the percentage of each level;
• Experience of the workshop instructors/leaders in in the targeted content areas;
• A list of conferences where this workshop has been previously presented, including past AMIA meetings.

Systems demonstrations illustrate one or more aspects of a leading-edge system that is in use, under development, or at a testing or prototype stage. Each demonstration is 30 minutes long including questions and comments.

Your uploaded systems demonstration manuscript file must be submitted as a one-page (U.S. Letter; 8.5 x 11 inch) document and must include:

• The names, academic degree(s), affiliations, and locations (city, state, and country, if international) of all presenters
• An abstract of 50-75 words summarizing the proposal, which will also be entered into a text box at the beginning of the online form to be used in the online and print programs. The abstract does NOT have to be part of the document, but must be entered on the submission website in the Abstract box in Step 2. (Please DO NOT copy and paste the entire one-page document into that box)
• A description of the specific purposes of the system, service, or project; the problems in health care practice, biomedicine, or research in informatics that it is designed to address; and the purpose or features of the system, service, or project that make it particularly innovative
• A statement of the degree to which the system or service has been deployed, as of the date of submitting the proposal

The format of credentials and other author information appearing in the online and printed materials is subject to revision by the AMIA office. It is the responsibility of the first author of each proposal to provide full and accurate information about all co-authors on the submission.