The NAM launched the Clinician Well-Being Collaborative in 2017 to reverse trends in health worker burnout. In October 2022, the NAM released the National Plan for Health Workforce Well-Being to drive collective action to strengthen health workforce well-being and restore the health of the nation, as more nurses, physicians, and public health employees than ever are poised to leave their professions. This plan cited AMIA’s 25x5 work and AMIA endorsed this plan. The Change Maker Campaign aims to advance the National Plan Priority Areas and spark a national movement to support health workforce well-being. The campaign will provide a dynamic mechanism to facilitate information sharing and collaboration across ongoing initiatives, document their impact, and amplify effective solutions to common challenges.